DPM1

GENE INFORMATION

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Gene name

DPM1 (HGNC Symbol)

Synonyms

CDGIE, MPDS

Description

dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit (HGNC Symbol)

Entrez gene summary

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q13.13

Chromosome location (bp)

49551404 - 49575092

Ensembl

ENSG00000000419 (version 73.37)

Entrez gene

8813

UniProt

O60762 (UniProt - Evidence at protein level)

neXtProt

NX_O60762

Antibodypedia

DPM1 antibodies
 

PROTEIN VIEW

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DPM1-001
 
DPM1-003
 
DPM1-004
 
DPM1-005
 
DPM1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DPM1-001 ENSP00000360644
ENST00000371588
O60762
Show all »
Show » Show » 260 29.6 No 0
DPM1-003 ENSP00000360640
ENST00000371584
Show » 295 33.2 No 0
DPM1-004 ENSP00000394921
ENST00000413082
Q5QPJ9
Show all »
221 25.1 No 0
DPM1-005 ENSP00000360638
ENST00000371582
Q5QPK2
Show all »
Show » 287 32.4 No 0
DPM1-201 ENSP00000360639
ENST00000371583
E9PHH5
Show all »
Show » 255 28.8 No 0