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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN NASOPHARYNX ORAL MUCOSA
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:19.0 nTPM
HPA:19.0 nTPM
GTEx:17.2 nTPM
FANTOM5:43.9 Scaled Tags Per Million

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 19.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 17.2
2666 Male, age 74, left hemisphere 19.0
2019 Male, age 18, unknown 18.7
1870 Female, age 42, unknown 18.0
2411 Female, age 72, unknown 17.7
2828 Female, age 72, unknown 17.7
1830 Male, age 51, unknown 17.5
1833 Male, age 53, unknown 17.4
1827 Male, age 72, unknown 16.1
2219 Male, age 76, both hemispheres 15.8
2586 Male, age 75, left hemisphere 14.3
Dorsal raphe nucleus
nTPM: 17.1
2016 Female, age 72, unknown 17.8
1828 Male, age 53, unknown 17.5
2750 Male, age 76, both hemispheres 17.4
2298 Female, age 72, unknown 16.7
2047 Male, age 72, unknown 16.3
Inferior colliculus
nTPM: 17.8
1890 Male, age 53, unknown 20.2
2097 Female, age 72, unknown 17.8
1848 Female, age 42, unknown 16.7
2849 Male, age 72, unknown 16.4
Median raphe nucleus
nTPM: 16.6
2220 Male, age 76, midline 16.6
Pedunculopontine tegmental nucleus
nTPM: 19.0
2338 Male, age 61, both hemispheres 23.4
2334 Male, age 80, both hemispheres 17.2
1921 Female, age 85, both hemispheres 16.4
Periaquaductal grey, anterior
nTPM: 17.1
2502 Female, age 75, unknown 18.8
1947 Male, age 18, unknown 16.4
1795 Male, age 51, unknown 16.0
Periaquaductal grey, dorsal
nTPM: 17.2
1831 Male, age 72, unknown 18.9
2464 Female, age 72, unknown 17.7
2850 Male, age 76, both hemispheres 16.2
1840 Male, age 53, unknown 16.1
Periaquaductal grey, lateral
nTPM: 16.8
2053 Male, age 18, unknown 17.1
2272 Male, age 74, both hemispheres 16.9
2140 Male, age 76, both hemispheres 16.4
Pretectal area
nTPM: 16.6
2316 Male, age 76, right hemisphere 18.0
1817 Female, age 42, unknown 17.7
1815 Male, age 53, unknown 16.8
1816 Male, age 51, unknown 16.5
2007 Male, age 72, unknown 16.5
2667 Female, age 75, unknown 16.5
1944 Female, age 72, unknown 16.4
2825 Male, age 18, unknown 16.4
2224 Female, age 72, unknown 16.2
2273 Male, age 74, both hemispheres 16.0
2407 Male, age 75, both hemispheres 15.2
Red nucleus
nTPM: 18.7
1821 Female, age 72, unknown 21.5
1904 Male, age 53, unknown 20.0
1954 Female, age 42, unknown 19.7
2823 Male, age 76, right hemisphere 19.5
2227 Male, age 72, unknown 19.2
2503 Female, age 72, unknown 19.2
2769 Male, age 72, unknown 19.0
2588 Male, age 74, left hemisphere 18.7
1865 Male, age 51, unknown 18.5
2785 Male, age 18, unknown 17.3
2725 Female, age 75, unknown 16.9
2584 Male, age 75, left hemisphere 15.5
Substantia nigra
nTPM: 18.7
2665 Male, age 74, both hemispheres 24.6
2409 Female, age 72, unknown 20.8
2590 Female, age 75, unknown 19.8
1851 Male, age 51, unknown 19.6
2241 Male, age 72, unknown 18.7
2699 Male, age 18, unknown 18.0
1889 Female, age 72, unknown 17.1
1916 Female, age 42, unknown 16.8
1941 Male, age 53, unknown 15.8
2583 Male, age 75, right hemisphere 15.7
Superior colliculus
nTPM: 16.8
2587 Male, age 74, left hemisphere 19.1
1895 Male, age 76, right hemisphere 17.9
2087 Female, age 72, unknown 17.9
1913 Female, age 42, unknown 17.0
1995 Male, age 72, unknown 17.0
2261 Male, age 18, unknown 16.7
1839 Male, age 51, unknown 16.6
1796 Male, age 53, unknown 16.3
2668 Female, age 75, unknown 15.6
2664 Male, age 75, both hemispheres 14.3
Ventral tegmental area
nTPM: 18.3
1915 Female, age 42, unknown 19.1
2410 Female, age 72, unknown 18.7
2218 Male, age 76, both hemispheres 18.5
2021 Male, age 53, unknown 18.2
1942 Male, age 51, unknown 18.0
2223 Female, age 72, unknown 17.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 17.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 17.2
Samples: 139

Max nTPM: 103.7
Min nTPM: 2.5
Std nTPM: 13.6
Median nTPM: 13.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 103.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 81.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 63.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 48.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 44.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 42.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 36.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 36.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 35.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 31.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 31.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 30.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 29.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 29.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 28.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 28.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 28.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 27.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 25.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 24.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 23.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 22.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 22.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 22.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 22.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 22.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 22.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 21.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 21.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 20.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 20.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 20.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 19.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 19.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 19.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 19.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 19.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 19.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 19.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 19.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 19.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 19.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 19.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 18.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 18.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 18.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 18.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 18.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 18.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 17.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 17.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 17.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 17.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 16.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 16.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 15.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 15.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 15.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 15.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 14.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 14.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 14.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 14.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 14.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 14.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 13.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 13.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 13.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 13.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 13.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 13.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 12.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 12.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 12.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 12.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 12.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 12.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 12.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 12.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 12.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 12.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 11.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 11.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 11.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 11.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 11.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 11.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 11.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 11.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 11.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 11.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 11.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 10.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 10.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 10.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 10.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 10.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 10.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 9.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 9.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 9.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 9.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 8.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 8.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 8.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 8.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 8.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 8.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 8.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 8.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 8.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 7.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 7.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 7.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 7.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 7.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 7.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 7.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 7.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 7.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 6.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 6.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 6.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 6.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 6.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 5.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 5.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 5.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 5.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 5.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 5.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 4.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 3.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 2.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 2.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 43.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 43.9
FF:10158-103A5 76 years, female 43.9

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