FUCA2

GENE INFORMATION

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Gene name

FUCA2 (HGNC Symbol)

Synonyms

dJ20N2.5, MGC1314

Description

Fucosidase, alpha-L- 2, plasma (HGNC Symbol)

Entrez gene summary

This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010]

Chromosome

6

Cytoband

q24.2

Chromosome location (bp)

143494811 - 143511690

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000001036 (version 78.38)

Entrez gene

2519

UniProt

Q9BTY2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BTY2

Antibodypedia

FUCA2 antibodies
 

PROTEIN VIEW

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FUCA2-001
 
FUCA2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FUCA2-001 ENSP00000002165
ENST00000002165
Q9BTY2
Show all »
Show » Show » 467 54.1 Yes 0
FUCA2-003 ENSP00000398119
ENST00000451668
Q7Z6V2
Show all »
Show » Show » 109 12.3 No 0