CD99

GENE INFORMATION

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Gene name

CD99 (HGNC Symbol)

Synonyms

MIC2

Description

CD99 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2013]

Chromosome

X (Chromosome progress)

Cytoband

p22.33

Chromosome location (bp)

2609220 - 2659350

Ensembl

ENSG00000002586 (version 73.37)

Entrez gene

4267

UniProt

P14209 (UniProt - Evidence at protein level)

neXtProt

NX_P14209

Antibodypedia

CD99 antibodies
 

PROTEIN VIEW

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CD99-001
 
CD99-002
 
CD99-003
 
CD99-004
 
CD99-005
 
CD99-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD99-001 ENSP00000370588
ENST00000381192
P14209
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Show » Show » 185 18.8 Yes 1
CD99-002 ENSP00000370573
ENST00000381180
A6NJT9
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Show » 76 8 Yes 0
CD99-003 ENSP00000370582
ENST00000381187
P14209
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Show » Show » 169 17.1 Yes 1
CD99-004 ENSP00000370579
ENST00000381184
A8MQT7
Show all »
Show » 177 17.7 Yes 1
CD99-005 ENSP00000405544
ENST00000449611
H7C2F2
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Show » 201 20.6 No 1
CD99-008 ENSP00000370570
ENST00000381177
A6NGF6
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61 6.9 No 0