CFLAR

GENE INFORMATION

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Gene name

CFLAR (HGNC Symbol)

Synonyms

c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT

Description

CASP8 and FADD-like apoptosis regulator (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]

Chromosome

2 (Chromosome progress)

Cytoband

q33.1

Chromosome location (bp)

201980827 - 202029033

Ensembl

ENSG00000003402 (version 73.37)

Entrez gene

8837

UniProt

O15519 (UniProt - Evidence at protein level)

neXtProt

NX_O15519

Antibodypedia

CFLAR antibodies
 

PROTEIN VIEW

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 « 
 
CFLAR-001
 
CFLAR-002
 
CFLAR-003
 
CFLAR-005
 
CFLAR-006
 
CFLAR-007
 
CFLAR-008
 
CFLAR-009
 
CFLAR-010
 
CFLAR-011
 
CFLAR-012
 
CFLAR-015
 
CFLAR-016
 
CFLAR-017
 
CFLAR-018
 
CFLAR-021
 
CFLAR-022
 
CFLAR-023
 
CFLAR-201
 
CFLAR-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CFLAR-001 ENSP00000312455
ENST00000309955
O15519
Show all »
Show » Show » 480 55.3 No 0
CFLAR-002 ENSP00000413270
ENST00000443227
O15519
Show all »
Show » Show » 384 44.1 No 0
CFLAR-003 ENSP00000339335
ENST00000341222
O15519
Show all »
Show » Show » 221 25.4 No 0
CFLAR-005 ENSP00000378580
ENST00000395148
E9PAP3
Show all »
Show » Show » 250 28.6 No 0
CFLAR-006 ENSP00000345807
ENST00000341582
O15519
Show all »
Show » Show » 445 51.3 No 0
CFLAR-007 ENSP00000342809
ENST00000342795
O15519
Show all »
Show » Show » 292 33.3 No 0
CFLAR-008 ENSP00000399420
ENST00000423241
O15519
Show all »
Show » Show » 480 55.3 No 0
CFLAR-009 ENSP00000398551
ENST00000439154
F8WBH9
Show all »
Show » 243 27.9 No 0
CFLAR-010 ENSP00000406775
ENST00000440180
O15519
Show all »
Show » Show » 221 25.4 No 0
CFLAR-011 ENSP00000411535
ENST00000457277
O15519
Show all »
Show » Show » 462 52.6 No 0
CFLAR-012 ENSP00000471805
ENST00000479953
O15519
Show all »
Show » Show » 366 41.3 No 0
CFLAR-015 ENSP00000411897
ENST00000441224
C9J408
Show all »
Show » 129 15 No 0
CFLAR-016 ENSP00000391029
ENST00000433445
C9J4Q0
Show all »
Show » 64 7.4 No 0
CFLAR-017 ENSP00000409570
ENST00000425030
C9JSU3
Show all »
Show » 62 7.1 No 0
CFLAR-018 ENSP00000412882
ENST00000417748
C9JV51
Show all »
Show » 118 13.7 No 0
CFLAR-021 ENSP00000469608
ENST00000494258
M0QY57
Show all »
Show » 117 13.2 No 0
CFLAR-022 ENSP00000471749
ENST00000470178
M0R1A8
Show all »
Show » 117 13.3 No 0
CFLAR-023 ENSP00000469917
ENST00000462763
M0QYM0
Show all »
Show » 168 19.1 No 0
CFLAR-201 ENSP00000339326
ENST00000340870
O15519
Show all »
Show » Show » 462 52.6 No 0
CFLAR-202 ENSP00000347757
ENST00000355558
C9JK38
Show all »
Show » 300 34.3 No 0