PDK4

GENE INFORMATION

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Gene name

PDK4

Synonyms

Description

pyruvate dehydrogenase kinase, isozyme 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

95212811 - 95225803

Ensembl

ENSG00000004799 (version 73.37)

Entrez gene

5166

UniProt

Q16654 (UniProt - Evidence at protein level)

neXtProt

NX_Q16654

Antibodypedia

PDK4 antibodies
 

PROTEIN VIEW

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PDK4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDK4-001 ENSP00000005178
ENST00000005178
Q16654
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