LIG3

GENE INFORMATION

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Gene name

LIG3 (HGNC Symbol)

Synonyms

LIG2

Description

ligase III, DNA, ATP-dependent (HGNC Symbol)

Entrez gene summary

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

33307513 - 33332083

Ensembl

ENSG00000005156 (version 73.37)

Entrez gene

3980

UniProt

P49916 (UniProt - Evidence at protein level)

neXtProt

NX_P49916

Antibodypedia

LIG3 antibodies
 

PROTEIN VIEW

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LIG3-001
 
LIG3-002
 
LIG3-005
 
LIG3-006
 
LIG3-007
 
LIG3-009
 
LIG3-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LIG3-001 ENSP00000367787
ENST00000378526
P49916
Show all »
Show » Show » 1009 112.9 No 0
LIG3-002 ENSP00000262327
ENST00000262327
P49916
Show all »
Show » Show » 949 106 No 0
LIG3-005 ENSP00000468479
ENST00000585941
K7ERZ5
Show all »
Show » 545 61.7 No 0
LIG3-006 ENSP00000467063
ENST00000592690
K7ENR9
Show all »
Show » 207 23 No 0
LIG3-007 ENSP00000467757
ENST00000585740
K7EQB6
Show all »
Show » 185 20.9 No 0
LIG3-009 ENSP00000466278
ENST00000588109
38 4.3 No 0
LIG3-015 ENSP00000465288
ENST00000585370
36 4.1 No 0