Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Nucleoli

Additional location(s)

Mitochondria 

Staining summary

Localized to nucleoli and mitochondria.

Reliability (APE)

Very low

Antibodies in assay

HPA024662, HPA025244
 

Antibody HPA024662

 

Antibody HPA025244

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Nucleoli, Mitochondria  

Staining characteristics

  

Staining intensity

Weak Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data or partly supported and partly conflicted, but showing dissimilar staining to ≥1 other antibody.
 
No staining.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

Nucleoli Aggresome 

Staining characteristics

  

Staining intensity

Weak Moderate 

Validation

Location not consistent with experimental gene/protein characterization data and showing dissimilar staining to ≥1 other antibody.
 
Location not consistent with experimental gene/protein characterization data and showing dissimilar staining to ≥1 other antibody.
 

Comment

  

         Cell line U-251 MG

Toggle channels

 
 

Location(s)

Nucleoli  

Staining characteristics

  

Staining intensity

Strong Negative 

Validation

Location not consistent with experimental gene/protein characterization data and showing dissimilar staining to ≥1 other antibody.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in nucleoli & mitochondria.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in aggresome.
 

Summary

Staining of nucleoli in all three cell lines with additional staining of mitochondria in A-431.   Staining of aggresomes in U-2 OS  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is not consistent with literature.
 

Dictionary

Mitochondria
Nucleoli