PDK2

GENE INFORMATION

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Gene name

PDK2 (HGNC Symbol)

Synonyms

PDHK2

Description

pyruvate dehydrogenase kinase, isozyme 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Chromosome

17 (Chromosome progress)

Cytoband

q21.33

Chromosome location (bp)

48172101 - 48189516

Ensembl

ENSG00000005882 (version 73.37)

Entrez gene

5164

UniProt

Q15119 (UniProt - Evidence at protein level)

neXtProt

NX_Q15119

Antibodypedia

PDK2 antibodies
 

PROTEIN VIEW

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PDK2-001
 
PDK2-003
 
PDK2-008
 
PDK2-009
 
PDK2-012
 
PDK2-014
 
PDK2-016
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDK2-001 ENSP00000420927
ENST00000503176
Q15119
Show all »
Show » Show » 407 46.2 No 0
PDK2-003 ENSP00000007708
ENST00000007708
Q15119
Show all »
Show » Show » 343 38.9 No 0
PDK2-008 ENSP00000427682
ENST00000508030
D6RHG2
Show all »
Show » 129 14.9 No 0
PDK2-009 ENSP00000425265
ENST00000503614
D6RDN9
Show all »
Show » 259 29.4 No 0
PDK2-012 ENSP00000425615
ENST00000505440
D6RJH7
Show all »
Show » 141 16.2 No 0
PDK2-014 ENSP00000421178
ENST00000512238
D6RGV8
Show all »
Show » 98 11.5 No 0
PDK2-016 ENSP00000423310
ENST00000510219
160 18.6 No 0