MARK4

GENE INFORMATION

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Gene name

MARK4 (HGNC Symbol)

Synonyms

FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D

Description

MAP/microtubule affinity-regulating kinase 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

45582546 - 45808541

Ensembl

ENSG00000007047 (version 73.37)

Entrez gene

57787

UniProt

Q96L34 (UniProt - Evidence at protein level)

neXtProt

NX_Q96L34

Antibodypedia

MARK4 antibodies
 

PROTEIN VIEW

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MARK4-001
 
MARK4-002
 
MARK4-005
 
MARK4-006
 
MARK4-008
 
MARK4-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MARK4-001 ENSP00000262891
ENST00000262891
Q96L34
Show all »
Show » Show » 752 82.5 No 0
MARK4-002 ENSP00000300843
ENST00000300843
Q96L34
Show all »
Show » Show » 688 75.3 No 0
MARK4-005 ENSP00000466702
ENST00000592762
Q6IPE9
Show all »
Show » Show » 97 10.5 No 0
MARK4-006 ENSP00000465613
ENST00000590909
K7EKG8
Show all »
Show » 74 8.7 No 0
MARK4-008 ENSP00000466843
ENST00000592207
Show » 48 5.1 No 0
MARK4-010 ENSP00000465414
ENST00000587566
K7EK17
Show all »
Show » 62 7.2 No 0