CACNA2D2

GENE INFORMATION

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Gene name

CACNA2D2 (HGNC Symbol)

Synonyms

KIAA0558

Description

calcium channel, voltage-dependent, alpha 2/delta subunit 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p21.31

Chromosome location (bp)

50400233 - 50541675

Ensembl

ENSG00000007402 (version 73.37)

Entrez gene

9254

UniProt

Q9NY47 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NY47

Antibodypedia

CACNA2D2 antibodies
 

PROTEIN VIEW

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CACNA2D2-001
 
CACNA2D2-002
 
CACNA2D2-003
 
CACNA2D2-005
 
CACNA2D2-007
 
CACNA2D2-008
 
CACNA2D2-201
 
CACNA2D2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CACNA2D2-001 ENSP00000390329
ENST00000424201
Q9NY47
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Show » Show » 1143 129.1 No 0
CACNA2D2-002 ENSP00000266039
ENST00000266039
Q9NY47
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Show » Show » 1145 129.3 No 0
CACNA2D2-003 ENSP00000354228
ENST00000360963
Q9NY47
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Show » Show » 1076 122.1 No 0
CACNA2D2-005 ENSP00000418081
ENST00000479441
Q9NY47
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Show » Show » 1150 129.8 No 0
CACNA2D2-007 ENSP00000407393
ENST00000423994
C9JVC9
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Show » 1153 130.1 No 0
CACNA2D2-008 ENSP00000404631
ENST00000429770
C9JE82
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Show » 1144 129.2 No 0
CACNA2D2-201 ENSP00000378519
ENST00000395083
C9JHE6
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Show » 1146 129.4 No 0
CACNA2D2-202 ENSP00000390526
ENST00000435965
C9JGM2
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Show » 1153 130.1 No 0