PSMB1

GENE INFORMATION

? »

Gene name

PSMB1 (HGNC Symbol)

Synonyms

HC5, PMSB1

Description

proteasome (prosome, macropain) subunit, beta type, 1 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

q27

Chromosome location (bp)

170844205 - 170862429

Ensembl

ENSG00000008018 (version 73.37)

Entrez gene

5689

UniProt

P20618 (UniProt - Evidence at protein level)

neXtProt

NX_P20618

Antibodypedia

PSMB1 antibodies
 

PROTEIN VIEW

? »
 
 
 
PSMB1-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMB1-001 ENSP00000262193
ENST00000262193
P20618
Show all »
Show » Show » 241 26.5 No 0