Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Nucleus but not nucleoli, Cytoplasm

Additional location(s)

 

Staining summary

Localized to nucleus and cytoplasm.

Reliability (APE)

Medium

Antibodies in assay

HPA000397, CAB021929
 

Antibody HPA000397

 

Antibody CAB021929

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Cytoplasm Nucleus but not nucleoli, Cytoplasm 

Staining characteristics

Granular  

Staining intensity

Moderate Weak 

Validation

Location not consistent with experimental gene/protein characterization data, but supported by ≥1 other antibody.
 
Location not consistent with experimental gene/protein characterization data, but supported by ≥1 other antibody.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Cytoplasm Nucleus but not nucleoli, Cytoplasm 

Staining characteristics

Granular  

Staining intensity

Weak Weak 

Validation

Location not consistent with experimental gene/protein characterization data, but supported by ≥1 other antibody.
 
Location not consistent with experimental gene/protein characterization data, but supported by ≥1 other antibody.
 

Comment

  

         Cell line U-251 MG

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Cytoplasm Nucleus but not nucleoli, Cytoplasm 

Staining characteristics

Granular  

Staining intensity

Weak Weak 

Validation

Location not consistent with experimental gene/protein characterization data, but supported by ≥1 other antibody.
 
Location not consistent with experimental gene/protein characterization data, but supported by ≥1 other antibody.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm.
 

Summary

Weak granular staining of cytoplasm and nucleus.   Staining of cytoplasm and nucleus in all three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Nucleus but not nucleoli