CDKL5

GENE INFORMATION

? »

Gene name

CDKL5 (HGNC Symbol)

Synonyms

EIEE2, STK9

Description

Cyclin-dependent kinase-like 5 (HGNC Symbol)

Entrez gene summary

This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p22.13

Chromosome location (bp)

18443703 - 18671749

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000008086 (version 75.37)

Entrez gene

6792

UniProt

O76039 (UniProt - Evidence at protein level)

neXtProt

NX_O76039

Antibodypedia

CDKL5 antibodies
 

PROTEIN VIEW

? »
 
 
 
CDKL5-001
 
CDKL5-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDKL5-001 ENSP00000369325
ENST00000379989
O76039
Show all »
Show » Show » 1030 115.5 No 0
CDKL5-002 ENSP00000369332
ENST00000379996
O76039
Show all »
Show » Show » 1030 115.5 No 0