GIPR

GENE INFORMATION

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Gene name

GIPR

Synonyms

Description

gastric inhibitory polypeptide receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

46171502 - 46186982

Ensembl

ENSG00000010310 (version 73.37)

Entrez gene

2696

UniProt

P48546 (UniProt - Evidence at protein level)

neXtProt

NX_P48546

Antibodypedia

GIPR antibodies
 

PROTEIN VIEW

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GIPR-001
 
GIPR-002
 
GIPR-003
 
GIPR-004
 
GIPR-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GIPR-001 ENSP00000467494
ENST00000590918
P48546
Show all »
Show » Show » 466 53.2 Yes 7
GIPR-002 ENSP00000263281
ENST00000263281
Show » Show » 419 48.1 Yes 7
GIPR-003 ENSP00000305321
ENST00000304207
B7WP14
Show all »
Show » Show » 430 49.1 Yes 7
GIPR-004 ENSP00000467342
ENST00000585889
K7EPD9
Show all »
Show » Show » 265 30.1 Yes 3
GIPR-005 ENSP00000465385
ENST00000591322
17 1.9 No 0