BTK

GENE INFORMATION

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Gene name

BTK (HGNC Symbol)

Synonyms

AGMX1, ATK, IMD1, PSCTK1, XLA

Description

Bruton agammaglobulinemia tyrosine kinase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq, Nov 2008]

Chromosome

X (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

100604435 - 100641183

Ensembl

ENSG00000010671 (version 73.37)

Entrez gene

695

UniProt

Q06187 (UniProt - Evidence at protein level)

neXtProt

NX_Q06187

Antibodypedia

BTK antibodies
 

PROTEIN VIEW

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BTK-006
 
BTK-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BTK-006 ENSP00000308176
ENST00000308731
Q06187
Show all »
Show » Show » 659 76.3 No 0
BTK-201 ENSP00000361971
ENST00000372880
Q5JY90
Show all »
Show » Show » 483 55.9 No 0