KDM5D

GENERAL INFORMATION

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Gene name

KDM5D

Gene description

Lysine (K)-specific demethylase 5D

Protein class

Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA049086 , HPA060807
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

KDM5D (HGNC Symbol)

Synonyms

HY, HYA, JARID1D, KIAA0234, SMCY

Description

Lysine (K)-specific demethylase 5D (HGNC Symbol)

Entrez gene summary

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Chromosome

Y

Cytoband

q11.223

Chromosome location (bp)

19703865 - 19744939

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000012817 (version 78.38)

Entrez gene

8284

UniProt

Q9BY66 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BY66

Antibodypedia

KDM5D antibodies


PROTEIN BROWSER

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ENST00000317961
 
ENST00000382806
 
ENST00000415360
 
ENST00000440077
 
ENST00000447300
 
ENST00000541639
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KDM5D-001 ENSP00000322408
ENST00000317961
Q9BY66
Show all »
Show » Show » 1539 174.1 No 0
KDM5D-002 ENSP00000372256
ENST00000382806
Q9BY66
Show all »
Show » Show » 1482 167.4 No 0
KDM5D-003 ENSP00000416377
ENST00000447300
C9JGA3
Show all »
Show » Show » 425 48.5 No 0
KDM5D-004 ENSP00000398543
ENST00000440077
E9PFH2
Show all »
Show » Show » 1476 166.9 No 0
KDM5D-009 ENSP00000389433
ENST00000415360
H7BZF9
Show all »
Show » Show » 293 32.2 No 0
KDM5D-201 ENSP00000444293
ENST00000541639
Q9BY66
Show all »
Show » Show » 1570 177.6 No 0