CLK1

GENE INFORMATION

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Gene name

CLK1

Synonyms

Description

CDC-like kinase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Chromosome

2 (Chromosome progress)

Cytoband

q33.1

Chromosome location (bp)

201717732 - 201729422

Ensembl

ENSG00000013441 (version 73.37)

Entrez gene

1195

UniProt

P49759 (UniProt - Evidence at protein level)

neXtProt

NX_P49759

Antibodypedia

CLK1 antibodies
 

PROTEIN VIEW

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CLK1-001
 
CLK1-003
 
CLK1-005
 
CLK1-006
 
CLK1-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLK1-001 ENSP00000326830
ENST00000321356
P49759
Show all »
Show » Show » 484 57.3 No 1
CLK1-003 ENSP00000400487
ENST00000432425
P49759
Show all »
Show » Show » 136 16.6 No 0
CLK1-005 ENSP00000386358
ENST00000409769
B8ZZR0
Show all »
Show » Show » 307 36.3 No 0
CLK1-006 ENSP00000386875
ENST00000409403
F8WBF5
Show all »
Show » 355 41.9 No 0
CLK1-007 ENSP00000394734
ENST00000434813
P49759
Show all »
Show » Show » 526 61.8 No 1