ISL1

GENE INFORMATION

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Gene name

ISL1 (HGNC Symbol)

Synonyms

Isl-1, ISLET1

Description

ISL LIM homeobox 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q11.1

Chromosome location (bp)

50678921 - 50690564

Ensembl

ENSG00000016082 (version 73.37)

Entrez gene

3670

UniProt

P61371 (UniProt - Evidence at protein level)

neXtProt

NX_P61371

Antibodypedia

ISL1 antibodies
 

PROTEIN VIEW

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ISL1-001
 
ISL1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ISL1-001 ENSP00000230658
ENST00000230658
P61371
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Show » Show » 349 39 No 0
ISL1-003 ENSP00000422676
ENST00000511384
D6RBJ1
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Show » 326 36.7 No 0