IGF1

GENE INFORMATION

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Gene name

IGF1 (HGNC Symbol)

Synonyms

IGF1A

Description

insulin-like growth factor 1 (somatomedin C) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

Chromosome

12 (Chromosome progress)

Cytoband

q23.2

Chromosome location (bp)

102789645 - 102874423

Ensembl

ENSG00000017427 (version 73.37)

Entrez gene

3479

UniProt

P05019 (UniProt - Evidence at protein level)

neXtProt

NX_P05019

Antibodypedia

IGF1 antibodies
 

PROTEIN VIEW

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IGF1-001
 
IGF1-002
 
IGF1-003
 
IGF1-004
 
IGF1-005
 
IGF1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGF1-001 ENSP00000337612
ENST00000337514
P05019
Show all »
Show » Show » 153 17 Yes 0
IGF1-002 ENSP00000302665
ENST00000307046
P05019
Show all »
Show » Show » 195 21.8 Yes 0
IGF1-003 ENSP00000376638
ENST00000392905
Q13429
Show all »
Show » Show » 139 15.6 Yes 0
IGF1-004 ENSP00000416811
ENST00000424202
P05019
Show all »
Show » Show » 137 15.2 Yes 0
IGF1-005 ENSP00000376637
ENST00000392904
P05019
Show all »
Show » Show » 158 17.8 Yes 0
IGF1-201 ENSP00000394999
ENST00000456098
P05019
Show all »
Show » Show » 158 17.8 Yes 0