AGPS

GENE INFORMATION

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Gene name

AGPS (HGNC Symbol)

Synonyms

ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY

Description

alkylglycerone phosphate synthase (HGNC Symbol)

Entrez gene summary

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q31.2

Chromosome location (bp)

178257372 - 178408564

Ensembl

ENSG00000018510 (version 73.37)

Entrez gene

8540

UniProt

O00116 (UniProt - Evidence at protein level)

neXtProt

NX_O00116

Antibodypedia

AGPS antibodies
 

PROTEIN VIEW

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AGPS-001
 
AGPS-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGPS-001 ENSP00000264167
ENST00000264167
O00116
Show all »
Show » Show » 658 72.9 Yes 0
AGPS-002 ENSP00000386688
ENST00000409888
B8ZZ81
Show all »
Show » 189 20.2 Yes 0