SNAI2

GENE INFORMATION

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Gene name

SNAI2 (HGNC Symbol)

Synonyms

SLUG, SLUGH1, SNAIL2

Description

Snail family zinc finger 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q11.21

Chromosome location (bp)

49830249 - 49834299

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000019549 (version 75.37)

Entrez gene

6591

UniProt

O43623 (UniProt - Evidence at protein level)

neXtProt

NX_O43623

Antibodypedia

SNAI2 antibodies
 

PROTEIN VIEW

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SNAI2-001
 
SNAI2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNAI2-001 ENSP00000380034
ENST00000396822
O43623
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SNAI2-201 ENSP00000020945
ENST00000020945
O43623
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Show » Show » 268 30 No 0