VIM

GENE INFORMATION

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Gene name

VIM

Synonyms

Description

vimentin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

Chromosome

10 (Chromosome progress)

Cytoband

p13

Chromosome location (bp)

17270258 - 17279592

Ensembl

ENSG00000026025 (version 73.37)

Entrez gene

7431

UniProt

P08670 (UniProt - Evidence at protein level)

neXtProt

NX_P08670

Antibodypedia

VIM antibodies
 

PROTEIN VIEW

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VIM-001
 
VIM-002
 
VIM-003
 
VIM-008
 
VIM-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VIM-001 ENSP00000224237
ENST00000224237
P08670
Show all »
Show » Show » 466 53.7 No 0
VIM-002 ENSP00000435613
ENST00000487938
B0YJC4
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Show » 431 49.7 No 0
VIM-003 ENSP00000431702
ENST00000469543
B0YJC5
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Show » 228 26.9 No 0
VIM-008 ENSP00000391842
ENST00000421459
Q5JVS8
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Show » 173 20 No 0
VIM-201 ENSP00000446007
ENST00000544301
P08670
Show all »
Show » Show » 466 53.7 No 0