CD44

GENE INFORMATION

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Gene name

CD44 (HGNC Symbol)

Synonyms

CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1

Description

CD44 molecule (Indian blood group) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

p13

Chromosome location (bp)

35160417 - 35253949

Ensembl

ENSG00000026508 (version 73.37)

Entrez gene

960

UniProt

P16070 (UniProt - Evidence at protein level)

neXtProt

NX_P16070

Antibodypedia

CD44 antibodies
 

PROTEIN VIEW

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CD44-001
 
CD44-002
 
CD44-003
 
CD44-004
 
CD44-005
 
CD44-006
 
CD44-007
 
CD44-008
 
CD44-009
 
CD44-011
 
CD44-015
 
CD44-019
 
CD44-024
 
CD44-026
 
CD44-028
 
CD44-030
 
CD44-032
 
CD44-033
 
CD44-034
 
CD44-035
 
CD44-036
 
CD44-037
 
CD44-038
 
CD44-039
 
CD44-040
 
CD44-041
 
CD44-201
 
CD44-202
 
CD44-203
 
CD44-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD44-001 ENSP00000398632
ENST00000428726
P16070
Show all »
Show » Show » 742 81.5 Yes 1
CD44-002 ENSP00000278386
ENST00000278386
P16070
Show all »
Show » Show » 139 15.6 Yes 0
CD44-003 ENSP00000263398
ENST00000263398
P16070
Show all »
Show » Show » 361 39.4 Yes 1
CD44-004 ENSP00000389830
ENST00000415148
P16070
Show all »
Show » Show » 699 76.6 Yes 1
CD44-005 ENSP00000392331
ENST00000433892
P16070
Show all »
Show » Show » 493 53.4 Yes 1
CD44-006 ENSP00000398099
ENST00000442151
C1PHC3
Show all »
Show » Show » 294 31.9 Yes 1
CD44-007 ENSP00000309732
ENST00000352818
P16070
Show all »
Show » Show » 340 37.3 Yes 1
CD44-008 ENSP00000404447
ENST00000434472
P16070
Show all »
Show » Show » 429 46.6 Yes 1
CD44-009 ENSP00000395953
ENST00000425428
Q86UZ1
Show all »
Show » Show » 80 8.9 Yes 0
CD44-011 ENSP00000435377
ENST00000526025
E9PKC6
Show all »
Show » Show » 78 8.8 Yes 0
CD44-015 ENSP00000434920
ENST00000525469
H0YE40
Show all »
Show » 82 9.1 No 0
CD44-019 ENSP00000432704
ENST00000526669
H0YD13
Show all »
Show » Show » 206 22.7 Yes 1
CD44-024 ENSP00000279452
ENST00000279452
H0Y2P0
Show all »
Show » Show » 287 31 No 1
CD44-026 ENSP00000436451
ENST00000524922
118 13.5 No 0
CD44-028 ENSP00000436623
ENST00000525685
B4XHE2
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243 26.7 No 0
CD44-030 ENSP00000433189
ENST00000531873
C0STK4
Show all »
Show » 195 21.2 No 0
CD44-032 ENSP00000278385
ENST00000278385
J3KN83
Show all »
Show » Show » 232 24.7 No 1
CD44-033 ENSP00000432405
ENST00000525211
H0YCV9
Show all »
Show » 249 27.3 No 0
CD44-034 ENSP00000435321
ENST00000533222
H0YEA1
Show all »
193 21 No 0
CD44-035 ENSP00000432718
ENST00000528455
C1PHC4
Show all »
Show » 230 25.7 No 0
CD44-036 ENSP00000436980
ENST00000525688
H0YF08
Show all »
Show » Show » 187 20.1 No 1
CD44-037 ENSP00000431860
ENST00000528672
H0YCL4
Show all »
195 21.5 No 0
CD44-038 ENSP00000434530
ENST00000527889
C1PHC4
Show all »
Show » 181 19.5 No 0
CD44-039 ENSP00000436549
ENST00000531110
H0YEU1
Show all »
249 27.3 No 0
CD44-040 ENSP00000434465
ENST00000526000
H0YDW7
Show all »
Show » 240 26 No 0
CD44-041 ENSP00000434418
ENST00000526553
191 21.1 No 0
CD44-201 ENSP00000353280
ENST00000360158
P16070
Show all »
Show » Show » 396 43.2 Yes 1
CD44-202 ENSP00000414567
ENST00000433354
E7EPC6
Show all »
Show » Show » 714 78.5 Yes 1
CD44-203 ENSP00000403990
ENST00000437706
P16070
Show all »
Show » Show » 674 74.4 Yes 1
CD44-204 ENSP00000391008
ENST00000449691
P16070
Show all »
Show » Show » 699 76.7 Yes 1