BTN3A1

GENE INFORMATION

? »

Gene name

BTN3A1 (HGNC Symbol)

Synonyms

BT3.1, BTF5, CD277

Description

butyrophilin, subfamily 3, member A1 (HGNC Symbol)

Entrez gene summary

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

Chromosome

6 (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

26402465 - 26415444

Ensembl

ENSG00000026950 (version 73.37)

Entrez gene

11119

UniProt

O00481 (UniProt - Evidence at protein level)

neXtProt

NX_O00481

Antibodypedia

BTN3A1 antibodies
 

PROTEIN VIEW

? »
 
 
 
BTN3A1-001
 
BTN3A1-002
 
BTN3A1-005
 
BTN3A1-006
 
BTN3A1-007
 
BTN3A1-009
 
BTN3A1-010
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BTN3A1-001 ENSP00000289361
ENST00000289361
O00481
Show all »
Show » Show » 513 57.7 Yes 1
BTN3A1-002 ENSP00000420010
ENST00000476549
O00481
Show all »
Show » Show » 352 39.4 Yes 1
BTN3A1-005 ENSP00000399393
ENST00000427334
A6PVC0
Show all »
Show » 43 4.7 Yes 0
BTN3A1-006 ENSP00000406667
ENST00000414912
O00481
Show all »
Show » Show » 461 52 Yes 1
BTN3A1-007 ENSP00000396684
ENST00000425234
O00481
Show all »
Show » Show » 378 41.8 Yes 1
BTN3A1-009 ENSP00000394937
ENST00000450085
E7EPR2
Show all »
Show » 119 13 Yes 0
BTN3A1-010 ENSP00000427013
ENST00000506698
E9PFB8
Show all »
Show » 92 10.2 Yes 0