IFNGR1

GENE INFORMATION

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Gene name

IFNGR1 (HGNC Symbol)

Synonyms

CD119, IFNGR

Description

interferon gamma receptor 1 (HGNC Symbol)

Entrez gene summary

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

137518621 - 137540586

Ensembl

ENSG00000027697 (version 73.37)

Entrez gene

3459

UniProt

P15260 (UniProt - Evidence at protein level)

neXtProt

NX_P15260

Antibodypedia

IFNGR1 antibodies
 

PROTEIN VIEW

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IFNGR1-001
 
IFNGR1-002
 
IFNGR1-003
 
IFNGR1-201
 
IFNGR1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IFNGR1-001 ENSP00000356713
ENST00000367739
P15260
Show all »
Show » Show » 489 54.4 Yes 1
IFNGR1-002 ENSP00000389249
ENST00000458076
Q5TFC9
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Show » 210 23.7 Yes 0
IFNGR1-003 ENSP00000394230
ENST00000414770
Q5TFD1
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Show » 161 18.6 No 0
IFNGR1-201 ENSP00000356709
ENST00000367735
B4DFT7
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Show » 186 21.5 No 0
IFNGR1-202 ENSP00000443282
ENST00000543628
F5H5M7
Show all »
Show » Show » 461 51.5 No 1