ARNTL2

GENE INFORMATION

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Gene name

ARNTL2 (HGNC Symbol)

Synonyms

bHLHe6, BMAL2, CLIF, MOP9, PASD9

Description

aryl hydrocarbon receptor nuclear translocator-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

12 (Chromosome progress)

Cytoband

p11.23

Chromosome location (bp)

27485787 - 27576241

Ensembl

ENSG00000029153 (version 73.37)

Entrez gene

56938

UniProt

Q8WYA1 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WYA1

Antibodypedia

ARNTL2 antibodies
 

PROTEIN VIEW

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ARNTL2-001
 
ARNTL2-002
 
ARNTL2-003
 
ARNTL2-004
 
ARNTL2-005
 
ARNTL2-006
 
ARNTL2-007
 
ARNTL2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARNTL2-001 ENSP00000266503
ENST00000266503
Q8WYA1
Show all »
Show » Show » 636 70.9 No 0
ARNTL2-002 ENSP00000442438
ENST00000544915
Q8WYA1
Show all »
Show » Show » 602 67.2 No 0
ARNTL2-003 ENSP00000438545
ENST00000546179
Q8WYA1
Show all »
Show » Show » 540 60.4 No 0
ARNTL2-004 ENSP00000379238
ENST00000395901
Q8WYA1
Show all »
Show » Show » 599 66.5 No 0
ARNTL2-005 ENSP00000312247
ENST00000311001
Q8WYA1
Show all »
Show » Show » 622 69.2 No 0
ARNTL2-006 ENSP00000261178
ENST00000261178
Q8WYA1
Show all »
Show » Show » 588 65.6 No 0
ARNTL2-007 ENSP00000445836
ENST00000542388
Q8WYA1
Show all »
Show » Show » 551 61.8 No 0
ARNTL2-008 ENSP00000400185
ENST00000457040
Show » 588 65.6 No 0