The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Moderate to strong cytoplasmic positivity was observed in most normal tissues. Squamous epithelial were negative.
Normal tissues showed moderate cytoplasmic staining. Lymphoid cells, urothelium, breast, gall bladder, fallopian tube and trophoblastic cells displayed strong cytoplasmic immunoreactivity. Glial cells in CNS, myocytes and skin was weakly stained or negative.
Moderate cytoplasmic immunoreactivity was observed in a majority of normal tissues. Breast glands, Purkinje cells and subsets of lymphoid reaction center cells were strongly stained.
Most normal cells showed moderate cytoplasmic positivity. Hepatocytes, squamous epithelia and myocytes were weakly stained or negative.