BAK1

GENE INFORMATION

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Gene name

BAK1 (HGNC Symbol)

Synonyms

BAK, BCL2L7, CDN1

Description

BCL2-antagonist/killer 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p21.31

Chromosome location (bp)

33540329 - 33548019

Ensembl

ENSG00000030110 (version 73.37)

Entrez gene

578

UniProt

Q16611 (UniProt - Evidence at protein level)

neXtProt

NX_Q16611

Antibodypedia

BAK1 antibodies
 

PROTEIN VIEW

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BAK1-002
 
BAK1-201
 
BAK1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BAK1-002 ENSP00000363591
ENST00000374467
Q16611
Show all »
Show » Show » 211 23.4 No 2
BAK1-201 ENSP00000353878
ENST00000360661
Q16611
Show all »
Show » Show » 211 23.4 No 2
BAK1-202 ENSP00000391258
ENST00000442998
C0H5Y7
Show all »
Show » Show » 153 16.9 No 1