RNF19A

GENE INFORMATION

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Gene name

RNF19A (HGNC Symbol)

Synonyms

DKFZp566B1346, dorfin, RNF19

Description

ring finger protein 19A, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

8 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

101269288 - 101348446

Ensembl

ENSG00000034677 (version 73.37)

Entrez gene

25897

UniProt

Q9NV58 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NV58

Antibodypedia

RNF19A antibodies
 

PROTEIN VIEW

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RNF19A-001
 
RNF19A-002
 
RNF19A-003
 
RNF19A-004
 
RNF19A-009
 
RNF19A-010
 
RNF19A-012
 
RNF19A-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RNF19A-001 ENSP00000342667
ENST00000341084
Q9NV58
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Show » Show » 838 90.7 No 2
RNF19A-002 ENSP00000429161
ENST00000517584
Q9NV58
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Show » 58 6.5 No 0
RNF19A-003 ENSP00000428968
ENST00000519449
Q9NV58
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Show » Show » 838 90.7 No 2
RNF19A-004 ENSP00000397305
ENST00000432381
A3KCU8
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89 10 No 0
RNF19A-009 ENSP00000431077
ENST00000519527
E7ETB2
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165 18.5 No 0
RNF19A-010 ENSP00000429841
ENST00000522369
E7EQ63
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113 12.5 No 0
RNF19A-012 ENSP00000429549
ENST00000523167
E7EQV8
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156 17.4 No 0
RNF19A-015 ENSP00000430553
ENST00000523481
15 1.8 No 0