SLC18A1

GENE INFORMATION

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Gene name

SLC18A1 (HGNC Symbol)

Synonyms

CGAT, VAT1, VMAT1

Description

solute carrier family 18 (vesicular monoamine), member 1 (HGNC Symbol)

Entrez gene summary

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]

Chromosome

8 (Chromosome progress)

Cytoband

p21.3

Chromosome location (bp)

20002366 - 20040717

Ensembl

ENSG00000036565 (version 73.37)

Entrez gene

6570

UniProt

P54219 (UniProt - Evidence at transcript level)

neXtProt

NX_P54219

Antibodypedia

SLC18A1 antibodies
 

PROTEIN VIEW

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SLC18A1-001
 
SLC18A1-002
 
SLC18A1-003
 
SLC18A1-004
 
SLC18A1-005
 
SLC18A1-008
 
SLC18A1-201
 
SLC18A1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC18A1-001 ENSP00000276373
ENST00000276373
P54219
Show all »
Show » Show » 525 56.3 No >9
SLC18A1-002 ENSP00000265808
ENST00000265808
P54219
Show all »
Show » Show » 493 52.7 No >9
SLC18A1-003 ENSP00000429664
ENST00000519026
P54219
Show all »
Show » Show » 493 52.7 No >9
SLC18A1-004 ENSP00000428001
ENST00000517776
Q96GL6
Show all »
Show » Show » 385 41.2 No >9
SLC18A1-005 ENSP00000428999
ENST00000522513
E5RK12
Show all »
Show » Show » 258 27.7 No 4
SLC18A1-008 ENSP00000371021
ENST00000381608
P54219
Show all »
Show » Show » 472 50 No >9
SLC18A1-201 ENSP00000413361
ENST00000437980
P54219
Show all »
Show » Show » 472 50 No >9
SLC18A1-202 ENSP00000387549
ENST00000440926
P54219
Show all »
Show » Show » 525 56.3 No >9