CASR

TISSUE ATLAS

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Gene description

Calcium-sensing receptor

RNA tissue category

Mixed.

Protein summary

Detected at High or Medium expression level in 8 of 77 analyzed normal tissue cell types.

Protein expression

Strong cytoplasmic and membranous staining was observed in pancreatic ducts, parathyroid gland and a subset of renal tubules while the gall bladder and subsets of cells in the gastrointestinal tract showed weak to moderate staining. Stratum granulosum in skin was strongly stained. Remaining normal tissues were generally negative.

Protein class

G-protein coupled receptors, Potential transmembrane proteins, Transporters

Protein evidence

High

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx N/A
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA039686