BEST2

GENE INFORMATION

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Gene name

BEST2 (HGNC Symbol)

Synonyms

FLJ20132, VMD2L1

Description

bestrophin 2 (HGNC Symbol)

Entrez gene summary

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

12862516 - 12869272

Ensembl

ENSG00000039987 (version 73.37)

Entrez gene

54831

UniProt

Q8NFU1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NFU1

Antibodypedia

BEST2 antibodies
 

PROTEIN VIEW

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BEST2-001
 
BEST2-002
 
BEST2-003
 
BEST2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BEST2-001 ENSP00000447203
ENST00000553030
Q8NFU1
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Show » Show » 509 57.1 No 4
BEST2-002 ENSP00000448310
ENST00000549706
Q8NFU1
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Show » Show » 509 57.1 No 4
BEST2-003 ENSP00000449403
ENST00000552539
78 8.9 No 0
BEST2-201 ENSP00000042931
ENST00000042931
Q8NFU1
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Show » Show » 509 57.1 No 4