PSMA4

GENE INFORMATION

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Gene name

PSMA4 (HGNC Symbol)

Synonyms

HC9, HsT17706

Description

proteasome (prosome, macropain) subunit, alpha type, 4 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q25.1

Chromosome location (bp)

78832747 - 78841604

Ensembl

ENSG00000041357 (version 73.37)

Entrez gene

5685

UniProt

P25789 (UniProt - Evidence at protein level)

neXtProt

NX_P25789

Antibodypedia

PSMA4 antibodies
 

PROTEIN VIEW

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 « 
 
PSMA4-001
 
PSMA4-004
 
PSMA4-006
 
PSMA4-009
 
PSMA4-012
 
PSMA4-014
 
PSMA4-015
 
PSMA4-016
 
PSMA4-017
 
PSMA4-018
 
PSMA4-019
 
PSMA4-020
 
PSMA4-021
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMA4-001 ENSP00000044462
ENST00000044462
P25789
Show all »
Show » Show » 261 29.5 No 0
PSMA4-004 ENSP00000402118
ENST00000413382
P25789
Show all »
Show » Show » 190 21.4 No 0
PSMA4-006 ENSP00000453887
ENST00000559082
P25789
Show all »
Show » Show » 261 29.5 No 0
PSMA4-009 ENSP00000453829
ENST00000560217
H0YN18
Show all »
Show » 230 26.3 No 0
PSMA4-012 ENSP00000453080
ENST00000560737
H0YL69
Show all »
Show » 236 26.4 No 0
PSMA4-014 ENSP00000452936
ENST00000559948
H0YKT8
Show all »
Show » 182 20.1 No 0
PSMA4-015 ENSP00000453802
ENST00000559365
H0YMZ1
Show all »
Show » 221 24.6 No 0
PSMA4-016 ENSP00000453523
ENST00000559437
H0YMA1
Show all »
Show » 209 23.3 No 0
PSMA4-017 ENSP00000453323
ENST00000558341
H0YLS6
Show all »
Show » 125 13.9 No 0
PSMA4-018 ENSP00000453621
ENST00000559146
H0YMI6
Show all »
Show » 183 20.5 No 0
PSMA4-019 ENSP00000453145
ENST00000558281
H0YLC2
Show all »
Show » 174 19.7 No 0
PSMA4-020 ENSP00000452917
ENST00000559154
H0YKS0
Show all »
Show » 122 13.6 No 0
PSMA4-021 ENSP00000453758
ENST00000558094
H0YMV3
Show all »
Show » 86 9.9 No 0