ADAM28

GENE INFORMATION

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Gene name

ADAM28 (HGNC Symbol)

Synonyms

ADAM23, eMDCII, MDC-Lm, MDC-Ls

Description

ADAM metallopeptidase domain 28 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform. [provided by RefSeq, Jul 2008]

Chromosome

8 (Chromosome progress)

Cytoband

p21.2

Chromosome location (bp)

24151553 - 24216531

Ensembl

ENSG00000042980 (version 73.37)

Entrez gene

10863

UniProt

Q9UKQ2 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UKQ2

Antibodypedia

ADAM28 antibodies
 

PROTEIN VIEW

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ADAM28-001
 
ADAM28-002
 
ADAM28-003
 
ADAM28-004
 
ADAM28-009
 
ADAM28-011
 
ADAM28-201
 
ADAM28-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM28-001 ENSP00000265769
ENST00000265769
Q9UKQ2
Show all »
Show » Show » 775 87.1 Yes 1
ADAM28-002 ENSP00000393699
ENST00000437154
Q9UKQ2
Show all »
Show » Show » 540 61.2 Yes 0
ADAM28-003 ENSP00000430085
ENST00000520448
E5RGY1
Show all »
Show » 217 25 Yes 0
ADAM28-004 ENSP00000431108
ENST00000523379
E5RJQ1
Show all »
58 6.5 Yes 0
ADAM28-009 ENSP00000430094
ENST00000518326
Show » Show » 174 19.2 No 2
ADAM28-011 ENSP00000429484
ENST00000521629
Show » Show » 387 42.7 No 1
ADAM28-201 ENSP00000380770
ENST00000397649
E7EMU1
Show all »
Show » 483 53.2 No 0
ADAM28-202 ENSP00000443743
ENST00000540823
B4DDY3
Show all »
Show » 307 34.1 No 0