EPHA3

GENE INFORMATION

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Gene name

EPHA3 (HGNC Symbol)

Synonyms

ETK, ETK1, HEK, HEK4, TYRO4

Description

EPH receptor A3 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p11.1

Chromosome location (bp)

89156674 - 89531284

Ensembl

ENSG00000044524 (version 73.37)

Entrez gene

2042

UniProt

P29320 (UniProt - Evidence at protein level)

neXtProt

NX_P29320

Antibodypedia

EPHA3 antibodies
 

PROTEIN VIEW

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EPHA3-001
 
EPHA3-002
 
EPHA3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHA3-001 ENSP00000337451
ENST00000336596
P29320
Show all »
Show » Show » 983 110.1 Yes 2
EPHA3-002 ENSP00000419190
ENST00000494014
C9JXA2
Show all »
Show » Show » 918 103.1 Yes 2
EPHA3-003 ENSP00000399926
ENST00000452448
P29320
Show all »
Show » Show » 539 60.9 Yes 0