GEMIN8

GENE INFORMATION

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Gene name

GEMIN8 (HGNC Symbol)

Synonyms

FAM51A1, FLJ20514

Description

gem (nuclear organelle) associated protein 8 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

Chromosome

X (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

14026398 - 14048012

Ensembl

ENSG00000046647 (version 73.37)

Entrez gene

54960

UniProt

Q9NWZ8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NWZ8

Antibodypedia

GEMIN8 antibodies
 

PROTEIN VIEW

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GEMIN8-001
 
GEMIN8-002
 
GEMIN8-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GEMIN8-001 ENSP00000369895
ENST00000380523
Q9NWZ8
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Show » 242 28.6 No 0
GEMIN8-002 ENSP00000381398
ENST00000398355
Q9NWZ8
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Show » 242 28.6 No 0
GEMIN8-003 ENSP00000369894
ENST00000332885
H7BYE2
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177 21 No 0