LTBP1

GENE INFORMATION

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Gene name

LTBP1

Synonyms

Description

latent transforming growth factor beta binding protein 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p22.3

Chromosome location (bp)

33172039 - 33624576

Ensembl

ENSG00000049323 (version 73.37)

Entrez gene

4052

UniProt

Q14766 (UniProt - Evidence at protein level)

neXtProt

NX_Q14766

Antibodypedia

LTBP1 antibodies
 

PROTEIN VIEW

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 « 
 
LTBP1-001
 
LTBP1-006
 
LTBP1-007
 
LTBP1-008
 
LTBP1-010
 
LTBP1-014
 
LTBP1-016
 
LTBP1-017
 
LTBP1-018
 
LTBP1-201
 
LTBP1-202
 
LTBP1-203
 
LTBP1-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LTBP1-001 ENSP00000385359
ENST00000404525
Q14766
Show all »
Show » 1342 147.2 Yes 0
LTBP1-006 ENSP00000415412
ENST00000413303
C9JDW2
Show all »
219 23.2 No 0
LTBP1-007 ENSP00000384091
ENST00000407925
Q14766
Show all »
Show » 1395 152.9 Yes 0
LTBP1-008 ENSP00000384373
ENST00000402934
C9JD84
Show all »
Show » 1340 147 Yes 0
LTBP1-010 ENSP00000395211
ENST00000422669
H7C0I7
Show all »
Show » 270 29.3 No 0
LTBP1-014 ENSP00000386043
ENST00000404816
Q14766
Show all »
Show » 1721 186.8 Yes 0
LTBP1-016 ENSP00000405993
ENST00000432635
H7C2H7
Show all »
Show » 101 10.9 No 0
LTBP1-017 ENSP00000388154
ENST00000415140
Show » 267 28.8 No 0
LTBP1-018 ENSP00000417591
ENST00000468091
H7C4L5
Show all »
221 23.5 No 0
LTBP1-201 ENSP00000272273
ENST00000272273
E7EUU6
Show all »
Show » 619 68.8 No 0
LTBP1-202 ENSP00000346467
ENST00000354476
Q14766
Show all »
Show » 1722 186.9 Yes 0
LTBP1-203 ENSP00000374653
ENST00000390003
Q14766
Show all »
Show » 1396 153 Yes 0
LTBP1-204 ENSP00000393057
ENST00000418533
E7EV71
Show all »
Show » 1353 148.4 Yes 0