ARHGEF5

GENE INFORMATION

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Gene name

ARHGEF5 (HGNC Symbol)

Synonyms

GEF5, P60, TIM, TIM1

Description

Rho guanine nucleotide exchange factor (GEF) 5 (HGNC Symbol)

Entrez gene summary

Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q35

Chromosome location (bp)

144052381 - 144077725

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000050327 (version 75.37)

Entrez gene

7984

UniProt

Q12774 (UniProt - Evidence at protein level)

neXtProt

NX_Q12774

Antibodypedia

ARHGEF5 antibodies
 

PROTEIN VIEW

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ARHGEF5-001
 
ARHGEF5-002
 
ARHGEF5-004
 
ARHGEF5-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF5-001 ENSP00000056217
ENST00000056217
Q12774
Show all »
Show » Show » 1597 176.8 No 0
ARHGEF5-002 ENSP00000418745
ENST00000474817
B3KQX6
Show all »
Show » Show » 797 89.1 No 0
ARHGEF5-004 ENSP00000417979
ENST00000498580
C9J591
Show all »
Show » 181 20.2 No 0
ARHGEF5-005 ENSP00000418227
ENST00000471847
Q12774
Show all »
Show » Show » 519 60.1 No 0