ANAPC4

GENE INFORMATION

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Gene name

ANAPC4 (HGNC Symbol)

Synonyms

APC4

Description

anaphase promoting complex subunit 4 (HGNC Symbol)

Entrez gene summary

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p15.2

Chromosome location (bp)

25378835 - 25420120

Ensembl

ENSG00000053900 (version 73.37)

Entrez gene

29945

UniProt

Q9UJX5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UJX5

Antibodypedia

ANAPC4 antibodies
 

PROTEIN VIEW

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ANAPC4-001
 
ANAPC4-002
 
ANAPC4-006
 
ANAPC4-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANAPC4-001 ENSP00000318775
ENST00000315368
Q9UJX5
Show all »
Show » Show » 808 92.1 No 0
ANAPC4-002 ENSP00000426654
ENST00000510092
E9PCR4
Show all »
Show » Show » 809 92.2 No 0
ANAPC4-006 ENSP00000421840
ENST00000505991
D6RAP6
Show all »
Show » 162 18.3 No 0
ANAPC4-008 ENSP00000426512
ENST00000505080
D6RFM7
Show all »
Show » 83 9.7 No 0