FOXC1

GENE INFORMATION

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Gene name

FOXC1 (HGNC Symbol)

Synonyms

ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1

Description

Forkhead box C1 (HGNC Symbol)

Entrez gene summary

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p25.3

Chromosome location (bp)

1610681 - 1614127

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000054598 (version 75.37)

Entrez gene

2296

UniProt

Q12948 (UniProt - Evidence at protein level)

neXtProt

NX_Q12948

Antibodypedia

FOXC1 antibodies
 

PROTEIN VIEW

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FOXC1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXC1-001 ENSP00000370256
ENST00000380874
Q12948
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