MRPL43

GENE INFORMATION

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Gene name

MRPL43 (HGNC Symbol)

Synonyms

bMRP36a

Description

mitochondrial ribosomal protein L43 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q24.31

Chromosome location (bp)

102729215 - 102747272

Ensembl

ENSG00000055950 (version 73.37)

Entrez gene

84545

UniProt

Q8N983 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N983

Antibodypedia

MRPL43 antibodies
 

PROTEIN VIEW

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MRPL43-001
 
MRPL43-002
 
MRPL43-004
 
MRPL43-006
 
MRPL43-007
 
MRPL43-008
 
MRPL43-009
 
MRPL43-010
 
MRPL43-012
 
MRPL43-013
 
MRPL43-201
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL43-001 ENSP00000359254
ENST00000370234
Q8N983
Show all »
Show » Show » 164 18.3 No 0
MRPL43-002 ENSP00000315364
ENST00000318325
Q8N983
Show all »
Show » Show » 215 23.4 No 0
MRPL43-004 ENSP00000315948
ENST00000318364
Q8N983
Show all »
Show » Show » 159 17.9 No 0
MRPL43-006 ENSP00000359262
ENST00000370242
B1AL06
Show all »
Show » 261 28.7 No 0
MRPL43-007 ENSP00000299179
ENST00000299179
Q8N983
Show all »
Show » Show » 202 22.6 No 0
MRPL43-008 ENSP00000359261
ENST00000370241
B1AL05
Show all »
184 20.5 No 0
MRPL43-009 ENSP00000408806
ENST00000448244
169 18.7 No 0
MRPL43-010 ENSP00000471004
ENST00000477279
M0R051
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44 4.7 No 0
MRPL43-012 ENSP00000359256
ENST00000370236
Q8N983
Show all »
Show » Show » 159 17.9 No 0
MRPL43-013 ENSP00000430369
ENST00000523148
148 16.6 No 0
MRPL43-201 ENSP00000339844
ENST00000342071
C9J5Q3
Show all »
Show » 235 25.9 No 0