PIGV

GENE INFORMATION

? »

Gene name

PIGV (HGNC Symbol)

Synonyms

FLJ20477

Description

phosphatidylinositol glycan anchor biosynthesis, class V (HGNC Symbol)

Entrez gene summary

This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Chromosome

1 (Chromosome progress)

Cytoband

p36.11

Chromosome location (bp)

27113963 - 27124889

Ensembl

ENSG00000060642 (version 73.37)

Entrez gene

55650

UniProt

Q9NUD9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NUD9

Antibodypedia

PIGV antibodies
 

PROTEIN VIEW

? »
 
 
 
PIGV-001
 
PIGV-002
 
PIGV-003
 
PIGV-004
 
PIGV-005
 
PIGV-006
 
PIGV-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIGV-001 ENSP00000078527
ENST00000078527
Q9NUD9
Show all »
Show » Show » 493 55.7 No 8
PIGV-002 ENSP00000363260
ENST00000374145
Q9NUD9
Show all »
Show » Show » 493 55.7 No 8
PIGV-003 ENSP00000399067
ENST00000430292
Q9NUD9
Show all »
Show » Show » 72 8.1 No 0
PIGV-004 ENSP00000436884
ENST00000472757
E9PQC7
Show all »
Show » Show » 74 8.3 No 0
PIGV-005 ENSP00000388425
ENST00000431541
Q9NUD9
Show all »
Show » Show » 121 13.5 No 0
PIGV-006 ENSP00000406080
ENST00000455364
Q9NUD9
Show all »
Show » Show » 182 20.1 No 3
PIGV-201 ENSP00000395156
ENST00000449950
B4DWP9
Show all »
Show » Show » 265 30.6 No 3