GUCY1B3

GENE INFORMATION

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Gene name

GUCY1B3 (HGNC Symbol)

Synonyms

GC-S-beta-1, GC-SB3, GUC1B3

Description

Guanylate cyclase 1, soluble, beta 3 (HGNC Symbol)

Entrez gene summary

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM, Mar 2008]

Chromosome

4

Cytoband

q32.1

Chromosome location (bp)

156680144 - 156728743

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000061918 (version 75.37)

Entrez gene

2983

UniProt

Q02153 (UniProt - Evidence at protein level)

neXtProt

NX_Q02153

Antibodypedia

GUCY1B3 antibodies
 

PROTEIN VIEW

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GUCY1B3-001
 
GUCY1B3-003
 
GUCY1B3-004
 
GUCY1B3-005
 
GUCY1B3-007
 
GUCY1B3-008
 
GUCY1B3-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GUCY1B3-001 ENSP00000427226
ENST00000505154
B7Z685
Show all »
Show » Show » 551 62.8 No 0
GUCY1B3-003 ENSP00000426786
ENST00000502959
E9PCN2
Show all »
Show » Show » 641 73.1 No 0
GUCY1B3-004 ENSP00000426319
ENST00000505764
B7Z426
Show all »
Show » Show » 599 68.2 No 0
GUCY1B3-005 ENSP00000422313
ENST00000507146
D6RC99
Show all »
Show » Show » 594 67.5 No 0
GUCY1B3-007 ENSP00000264424
ENST00000264424
Q02153
Show all »
Show » Show » 619 70.5 No 0
GUCY1B3-008 ENSP00000425065
ENST00000513437
B7Z685
Show all »
Show » Show » 551 62.8 No 0
GUCY1B3-010 ENSP00000420842
ENST00000503520
Q02153
Show all »
Show » Show » 586 66.7 No 0