U2AF2

GENE INFORMATION

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Gene name

U2AF2 (HGNC Symbol)

Synonyms

U2AF65

Description

U2 small nuclear RNA auxiliary factor 2 (HGNC Symbol)

Entrez gene summary

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.42

Chromosome location (bp)

56165512 - 56186081

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000063244 (version 75.37)

Entrez gene

11338

UniProt

P26368 (UniProt - Evidence at protein level)

neXtProt

NX_P26368

Antibodypedia

U2AF2 antibodies
 

PROTEIN VIEW

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U2AF2-001
 
U2AF2-002
 
U2AF2-003
 
U2AF2-007
 
U2AF2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

U2AF2-001 ENSP00000388475
ENST00000450554
P26368
Show all »
Show » Show » 471 53.1 No 0
U2AF2-002 ENSP00000307863
ENST00000308924
P26368
Show all »
Show » Show » 475 53.5 No 0
U2AF2-003 ENSP00000470020
ENST00000587196
Show » 51 5.4 No 0
U2AF2-007 ENSP00000466167
ENST00000592874
Show » 86 9.5 No 0
U2AF2-008 ENSP00000466935
ENST00000590551
K7ENG2
Show all »
Show » Show » 307 33.9 No 0