ABCA7

GENE INFORMATION

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Gene name

ABCA7 (HGNC Symbol)

Synonyms

ABCX

Description

ATP-binding cassette, sub-family A (ABC1), member 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

1040102 - 1065571

Ensembl

ENSG00000064687 (version 73.37)

Entrez gene

10347

UniProt

Q8IZY2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IZY2

Antibodypedia

ABCA7 antibodies
 

PROTEIN VIEW

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ABCA7-001
 
ABCA7-002
 
ABCA7-006
 
ABCA7-007
 
ABCA7-011
 
ABCA7-013
 
ABCA7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCA7-001 ENSP00000263094
ENST00000263094
Q8IZY2
Show all »
Show » Show » 2146 234.3 No >9
ABCA7-002 ENSP00000465322
ENST00000435683
Q8IZY2
Show all »
Show » Show » 2008 218.5 No >9
ABCA7-006 ENSP00000431473
ENST00000524850
E9PL63
Show all »
Show » Show » 164 18.4 No 0
ABCA7-007 ENSP00000433545
ENST00000531467
E9PKG5
Show all »
Show » 136 15.4 No 0
ABCA7-011 ENSP00000437311
ENST00000530092
61 6.5 No 0
ABCA7-013 ENSP00000432031
ENST00000525073
B3KUJ3
Show all »
Show » Show » 591 64.5 No 4
ABCA7-201 ENSP00000414062
ENST00000433129
Q8IZY2
Show all »
Show » Show » 2146 234.3 No >9