GLP2R

GENE INFORMATION

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Gene name

GLP2R

Synonyms

Description

glucagon-like peptide 2 receptor (HGNC Symbol)

Entrez gene summary

The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

9725523 - 9795419

Ensembl

ENSG00000065325 (version 73.37)

Entrez gene

9340

UniProt

O95838 (UniProt - Evidence at protein level)

neXtProt

NX_O95838

Antibodypedia

GLP2R antibodies
 

PROTEIN VIEW

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GLP2R-001
 
GLP2R-002
 
GLP2R-003
 
GLP2R-004
 
GLP2R-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GLP2R-001 ENSP00000262441
ENST00000262441
O95838
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Show » Show » 553 63 No 7
GLP2R-002 ENSP00000404471
ENST00000458005
E9PC86
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Show » Show » 228 26.4 No 5
GLP2R-003 ENSP00000458242
ENST00000574745
I3L0P5
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Show » Show » 373 43 No 7
GLP2R-004 ENSP00000458568
ENST00000574361
I3L151
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Show » 93 10 No 0
GLP2R-005 ENSP00000303605
ENST00000304773
E9PC86
Show all »
Show » Show » 118 13.9 No 3