The Human Protein Atlas

GENE INFORMATION

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Gene name	ERBB3 (HGNC Symbol)
Synonyms	HER3, LCCS2
Description	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Chromosome	12 (Chromosome progress)
Cytoband	q13.2
Chromosome location (bp)	56473641 - 56497289
Ensembl	ENSG00000065361 (version 69.37)
Entrez gene	2065
UniProt	P21860
neXtProt	NX_P21860
Antibodypedia	ERBB3 antibodies

PROTEIN VIEW

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ERBB3-001		ERBB3-003		ERBB3-004		ERBB3-005		ERBB3-006		ERBB3-009		ERBB3-010		ERBB3-011		ERBB3-012		ERBB3-014		ERBB3-020		ERBB3-023		ERBB3-024		ERBB3-201

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
ERBB3-001	ENSP00000267101 ENST00000267101	P21860 Show all » « Hide P21860 [Direct mapping] Receptor tyrosine-protein kinase erbB-3 F8VW56 [Target identity:43%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VYK4 [Target identity:34%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VRL0 [Target identity:9%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VW48 [Target identity:8%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VX90 [Target identity:8%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 Q9NNX2 [Target identity:4%; Query identity:100%] ErbB-3	Show » « Hide Kinases Tyr protein kinases Candidate cancer biomarkers Enzymes Transferases Potential transmembrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 1TM proteins predicted by MDM Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0003197 [endocardial cushion development] GO:0004672 [protein kinase activity] GO:0004714 [transmembrane receptor protein tyrosine kinase activity] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007162 [negative regulation of cell adhesion] GO:0007165 [signal transduction] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007409 [axonogenesis] GO:0007422 [peripheral nervous system development] GO:0007507 [heart development] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0009968 [negative regulation of signal transduction] GO:0014037 [Schwann cell differentiation] GO:0014065 [phosphatidylinositol 3-kinase cascade] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase cascade] GO:0016323 [basolateral plasma membrane] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0019838 [growth factor binding] GO:0021545 [cranial nerve development] GO:0030296 [protein tyrosine kinase activator activity] GO:0032869 [cellular response to insulin stimulus] GO:0042060 [wound healing] GO:0042127 [regulation of cell proliferation] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0042803 [protein homodimerization activity] GO:0043235 [receptor complex] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0046982 [protein heterodimerization activity] GO:0051048 [negative regulation of secretion] GO:0051402 [neuron apoptotic process] GO:0060056 [mammary gland involution] GO:0061098 [positive regulation of protein tyrosine kinase activity]	1342	148.1	Yes	1
ERBB3-003	ENSP00000447510 ENST00000551242	P21860 Show all » « Hide P21860 [Direct mapping] Receptor tyrosine-protein kinase erbB-3 F8VRL0 [Target identity:38%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VW48 [Target identity:35%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VX90 [Target identity:34%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3	Show » « Hide Kinases Tyr protein kinases Candidate cancer biomarkers Enzymes Transferases Potential transmembrane proteins MEMSAT3 predicted membrane proteins Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0003197 [endocardial cushion development] GO:0004714 [transmembrane receptor protein tyrosine kinase activity] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007162 [negative regulation of cell adhesion] GO:0007165 [signal transduction] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007409 [axonogenesis] GO:0007422 [peripheral nervous system development] GO:0007507 [heart development] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0009968 [negative regulation of signal transduction] GO:0014037 [Schwann cell differentiation] GO:0014065 [phosphatidylinositol 3-kinase cascade] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase cascade] GO:0016323 [basolateral plasma membrane] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0019838 [growth factor binding] GO:0021545 [cranial nerve development] GO:0030296 [protein tyrosine kinase activator activity] GO:0032869 [cellular response to insulin stimulus] GO:0042060 [wound healing] GO:0042127 [regulation of cell proliferation] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0042803 [protein homodimerization activity] GO:0043235 [receptor complex] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0046982 [protein heterodimerization activity] GO:0051048 [negative regulation of secretion] GO:0051402 [neuron apoptotic process] GO:0060056 [mammary gland involution] GO:0061098 [positive regulation of protein tyrosine kinase activity]	331	36.5	Yes	0
ERBB3-004	ENSP00000448729 ENST00000549832	B3KWG5 Show all » « Hide B3KWG5 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3; cDNA FLJ43038 fis, clone BRTHA3002955, highly similar to Receptor tyrosine-protein kinase erbB-3	Show » « Hide Potential transmembrane proteins SPOCTOPUS predicted membrane proteins	Show » « Hide GO:0004672 [protein kinase activity] GO:0004872 [receptor activity]	462	50.7	No	0
ERBB3-005	ENSP00000449129 ENST00000553131	F8VW56 Show all » « Hide F8VW56 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VYK4 [Target identity:79%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3		Show » « Hide GO:0003197 [endocardial cushion development] GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0007409 [axonogenesis] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0014037 [Schwann cell differentiation] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0021545 [cranial nerve development] GO:0032869 [cellular response to insulin stimulus] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0060056 [mammary gland involution]	583	64.3	No	0
ERBB3-006	ENSP00000415753 ENST00000411731	P21860 Show all » « Hide P21860 [Direct mapping] Receptor tyrosine-protein kinase erbB-3 F8VRL0 [Target identity:68%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3	Show » « Hide Kinases Tyr protein kinases Candidate cancer biomarkers Enzymes Transferases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0003197 [endocardial cushion development] GO:0004714 [transmembrane receptor protein tyrosine kinase activity] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007162 [negative regulation of cell adhesion] GO:0007165 [signal transduction] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007409 [axonogenesis] GO:0007422 [peripheral nervous system development] GO:0007507 [heart development] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0009968 [negative regulation of signal transduction] GO:0014037 [Schwann cell differentiation] GO:0014065 [phosphatidylinositol 3-kinase cascade] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase cascade] GO:0016323 [basolateral plasma membrane] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0019838 [growth factor binding] GO:0021545 [cranial nerve development] GO:0030296 [protein tyrosine kinase activator activity] GO:0032869 [cellular response to insulin stimulus] GO:0042060 [wound healing] GO:0042127 [regulation of cell proliferation] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0042803 [protein homodimerization activity] GO:0043235 [receptor complex] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0046982 [protein heterodimerization activity] GO:0051048 [negative regulation of secretion] GO:0051402 [neuron apoptotic process] GO:0060056 [mammary gland involution] GO:0061098 [positive regulation of protein tyrosine kinase activity]	183	20.1	Yes	0
ERBB3-009	ENSP00000448946 ENST00000550070	F8VYK4 Show all » « Hide F8VYK4 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3		Show » « Hide GO:0003197 [endocardial cushion development] GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0007409 [axonogenesis] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0014037 [Schwann cell differentiation] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0021545 [cranial nerve development] GO:0032869 [cellular response to insulin stimulus] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0060056 [mammary gland involution]	465	51.3	No	0
ERBB3-010	ENSP00000448636 ENST00000549282	F8VRL0 Show all » « Hide F8VRL0 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0003197 [endocardial cushion development] GO:0005634 [nucleus] GO:0007409 [axonogenesis] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0014037 [Schwann cell differentiation] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0021545 [cranial nerve development] GO:0032869 [cellular response to insulin stimulus] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0060056 [mammary gland involution]	126	14	Yes	0
ERBB3-011	ENSP00000449138 ENST00000549061	F8VW48 Show all » « Hide F8VW48 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VX90 [Target identity:99%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3		Show » « Hide GO:0003197 [endocardial cushion development] GO:0005634 [nucleus] GO:0007409 [axonogenesis] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0014037 [Schwann cell differentiation] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0021545 [cranial nerve development] GO:0032869 [cellular response to insulin stimulus] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0060056 [mammary gland involution]	116	13.3	No	0
ERBB3-012	ENSP00000446909 ENST00000552833				46	5.2	No	0
ERBB3-014	ENSP00000448671 ENST00000550869	F8VRI5 Show all » « Hide F8VRI5 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3			43	4.8	No	0
ERBB3-020	ENSP00000449713 ENST00000549672	F8VX90 Show all » « Hide F8VX90 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3		Show » « Hide GO:0003197 [endocardial cushion development] GO:0005634 [nucleus] GO:0007409 [axonogenesis] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0014037 [Schwann cell differentiation] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0021545 [cranial nerve development] GO:0032869 [cellular response to insulin stimulus] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0060056 [mammary gland involution]	115	13.2	No	0
ERBB3-023	ENSP00000448483 ENST00000551085	B4DGQ7 Show all » « Hide B4DGQ7 [Target identity:100%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3; cDNA FLJ59207, highly similar to Receptor tyrosine-protein kinase erbB-3 F8VRL0 [Target identity:13%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VW48 [Target identity:12%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VX90 [Target identity:12%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 Q9NNX2 [Target identity:6%; Query identity:100%] ErbB-3	Show » « Hide Potential transmembrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 1TM proteins predicted by MDM Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0003197 [endocardial cushion development] GO:0004714 [transmembrane receptor protein tyrosine kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007409 [axonogenesis] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0014037 [Schwann cell differentiation] GO:0016020 [membrane] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0021545 [cranial nerve development] GO:0032869 [cellular response to insulin stimulus] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0060056 [mammary gland involution]	921	101.8	Yes	1
ERBB3-024	ENSP00000408340 ENST00000415288	P21860 Show all » « Hide P21860 [Direct mapping] Receptor tyrosine-protein kinase erbB-3 F8VW56 [Target identity:45%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VYK4 [Target identity:36%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VW48 [Target identity:9%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VX90 [Target identity:8%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 Q9NNX2 [Target identity:4%; Query identity:100%] ErbB-3	Show » « Hide Kinases Tyr protein kinases Candidate cancer biomarkers Enzymes Transferases Potential transmembrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins 1TM proteins predicted by MDM Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0003197 [endocardial cushion development] GO:0004672 [protein kinase activity] GO:0004714 [transmembrane receptor protein tyrosine kinase activity] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007162 [negative regulation of cell adhesion] GO:0007165 [signal transduction] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007409 [axonogenesis] GO:0007422 [peripheral nervous system development] GO:0007507 [heart development] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0009968 [negative regulation of signal transduction] GO:0014037 [Schwann cell differentiation] GO:0014065 [phosphatidylinositol 3-kinase cascade] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase cascade] GO:0016323 [basolateral plasma membrane] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0019838 [growth factor binding] GO:0021545 [cranial nerve development] GO:0030296 [protein tyrosine kinase activator activity] GO:0032869 [cellular response to insulin stimulus] GO:0042060 [wound healing] GO:0042127 [regulation of cell proliferation] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0042803 [protein homodimerization activity] GO:0043235 [receptor complex] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0046982 [protein heterodimerization activity] GO:0051048 [negative regulation of secretion] GO:0051402 [neuron apoptotic process] GO:0060056 [mammary gland involution] GO:0061098 [positive regulation of protein tyrosine kinase activity]	1283	141.8	No	1
ERBB3-201	ENSP00000399178 ENST00000450146	P21860 Show all » « Hide P21860 [Direct mapping] Receptor tyrosine-protein kinase erbB-3 F8VW56 [Target identity:83%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3 F8VYK4 [Target identity:66%; Query identity:100%] Receptor tyrosine-protein kinase erbB-3	Show » « Hide Kinases Tyr protein kinases Candidate cancer biomarkers Enzymes Transferases Potential transmembrane proteins Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins 1TM proteins predicted by MDM Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0003197 [endocardial cushion development] GO:0004672 [protein kinase activity] GO:0004714 [transmembrane receptor protein tyrosine kinase activity] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0005887 [integral to plasma membrane] GO:0007162 [negative regulation of cell adhesion] GO:0007165 [signal transduction] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007409 [axonogenesis] GO:0007422 [peripheral nervous system development] GO:0007507 [heart development] GO:0007519 [skeletal muscle tissue development] GO:0007623 [circadian rhythm] GO:0009611 [response to wounding] GO:0009968 [negative regulation of signal transduction] GO:0014037 [Schwann cell differentiation] GO:0014065 [phosphatidylinositol 3-kinase cascade] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase cascade] GO:0016323 [basolateral plasma membrane] GO:0016324 [apical plasma membrane] GO:0016328 [lateral plasma membrane] GO:0019838 [growth factor binding] GO:0021545 [cranial nerve development] GO:0030296 [protein tyrosine kinase activator activity] GO:0032869 [cellular response to insulin stimulus] GO:0042060 [wound healing] GO:0042127 [regulation of cell proliferation] GO:0042476 [odontogenesis] GO:0042493 [response to drug] GO:0042803 [protein homodimerization activity] GO:0043235 [receptor complex] GO:0043524 [negative regulation of neuron apoptotic process] GO:0043586 [tongue development] GO:0045211 [postsynaptic membrane] GO:0046326 [positive regulation of glucose import] GO:0046982 [protein heterodimerization activity] GO:0051048 [negative regulation of secretion] GO:0051402 [neuron apoptotic process] GO:0060056 [mammary gland involution] GO:0061098 [positive regulation of protein tyrosine kinase activity]	699	77.4	No	1

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.