PDIA5

GENE INFORMATION

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Gene name

PDIA5 (HGNC Symbol)

Synonyms

FLJ30401, PDIR

Description

Protein disulfide isomerase family A, member 5 (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

3

Cytoband

q21.1

Chromosome location (bp)

122785909 - 122944074

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065485 (version 75.37)

Entrez gene

102465667

UniProt

Q14554 (UniProt - Evidence at protein level)

neXtProt

NX_Q14554

Antibodypedia

PDIA5 antibodies
 

PROTEIN VIEW

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PDIA5-001
 
PDIA5-002
 
PDIA5-004
 
PDIA5-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDIA5-001 ENSP00000323313
ENST00000316218
Q14554
Show all »
Show » Show » 519 59.6 Yes 0
PDIA5-002 ENSP00000417520
ENST00000489923
Q9BV43
Show all »
Show » Show » 262 30.1 Yes 0
PDIA5-004 ENSP00000419946
ENST00000484644
C9JY10
Show all »
Show » Show » 64 7.3 No 0
PDIA5-008 ENSP00000417199
ENST00000469649
Show » Show » 83 9.4 No 0