The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Most normal tissues displayed weak to moderate cytoplasmic positivity. Some tissues e.g. salivary gland and exocrine pancreas displayed membranous positivity. Strong staining was observed in the gastrointestinal tract and gall bladder. Most cells in CNS, pancreatic islet cells and lymphoid tissues were negative.
The large intestine showed strong staining in luminal membranes. A subset of lymphoid cells, bone marrow poietic cells, pancreatic islet cells and cells in urothelium exhibited strong cytoplasmic staining. Remaining normal cells were generally negative.
Normal tissues showed moderate cytoplasmic and nuclear staining. Strong immunoreactivity was for example observed in intestinal goblet cells. Lung, bile duct cells and pancreas were weakly stained or negative.